The follow-up appointment should be scheduled 3 to 7 days after taking misoprostol (MISO), and more than one follow-up appointment may be needed. The SOGC’s protocol on the provision of medication abortion by telemedicine advises 7 days[7], but some prescribers schedule the follow-up appointment as early as 3 days after MISO administration to avoid loss-of-contact and assess serum bhCG level. The actual practices depend on prescribers’ judgment and experiences.

During the virtual follow-up, prescribers should[7]:

  1. Review abortion experience and progress with patients, including dates of taking medication, side effects, bleeding pattern, pain, occurrence of expulsion, and any current pregnancy symptoms.
  2. Advise an urgent assessment or emergency visit if signs of ectopic pregnancy, pelvic infection, heavy bleeding, or excessive pain exist.
  3. If history suggests failed abortion or ongoing pregnancy: obtain ultrasound and consider an additional dose of MISO or procedural abortion.
  4. If history suggests successful abortion, no warning signs, and no current symptoms of pregnancy, normal bleeding and pain: arrange the blood test to confirm serum bhCG level if the appointment is in-person or instruct the patient to perform qualitative urine pregnancy test.

    Serum bhCG[4]: If the serum bhCG level drops by >50% at Day 3 after MISO or 80% at Day 7-14 after MIFE / MISO administration, the successful completion of abortion is confirmed and no further appointment is needed. Ultrasound should be ordered if 14 days have passed and a drop by 80% has not been reached.

    Urine bhCG[7]:
  5. Offer to discuss contraception options and provide emotional support if needed. Resources for emotional support include:
    • Exhale, a talk-line that provides emotional support, resources and information after abortion.
    • All-Options, a talk-line to discuss past or current experience with abortion, adoption and parenting for people in Canada and the United States (1-888-493-0092).

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