MIFE is metabolized by CYP3A4 and is also an irreversible competitive inhibitor of CYP3A4 and, to a lesser extent, of CYPs 1A, 2B, 2D6 and […]
Pharmacokinetics
MIFE taken orally shows non-linear pharmacokinetics. It is rapidly absorbed and distributed, reaching peak concentrations after 0.75 hours. It is 94-99% plasma-bound and is metabolized […]
Clinical assessments
Prescribers will provide clinical assessments prior to prescribing MIFE / MISO. With the new guideline by SOGC for the provision of medical abortion via telemedicine (MA), prescribers […]
Indication & Contraindications
Indication MIFE / MISO is indicated by [Health Canada](C17-2) for pregnancy termination up to 63 days as counted from the first day of the last […]
Efficacy & Safety
Efficacy: Side Effects and Complications[10]:
Mechanism of Action
In Canada, the medication abortion pills are packaged and sold as Mifegymiso. Mifegymiso comes in an outer white box, containing two smaller boxes: a green […]
